| Week | Player | Team | Pos | Pts |
| Rich Gannon | OAK | QB | 37 | |
| Jeff Garcia | SF | QB | 29 | |
| Terrell Owens | SF | WR | 29 | |
| Tim Brown | OAK | WR | 29 | |
| Eddie George | TEN | RB | 27 | |
| Daunte Culpepper | MIN | QB | 26 | |
| Ricky Williams | NO | RB | 23 | |
| Steve Beurlein | CAR | QB | 22 | |
| Shaun King | TB | QB | 22 | |
| Marvin Harrison | IND | WR | 21 | |
 | ||||
| Season | Player | Team | Pos | Pts |
| Kurt Warner | STL | QB | 129 | |
| Marshall Faulk | STL | RB | 122 | |
| Daunte Culpepper | MIN | QB | 120 | |
| Brian Griese | DEN | QB | 111 | |
| Peyton Manning | IND | QB | 106 | |
| Charlie Garner | SF | RB | 104 | |
| Jeff Garcia | SF | QB | 101 | |
| Stephen Davis | WAS | RB | 100 | |
| Rich Gannon | OAK | QB | 99 | |
| Jimmy Smith | JAX | WR | 98 |