| Week | Player | Team | Pos | Pts |
| Elvis Grbac | KC | QB | 34 | |
| Trent Green | STL | QB | 28 | |
| Rich Gannon | OAK | QB | 27 | |
| Lamar Smith | MIA | RB | 25 | |
| Derrick Alexander | KC | WR | 25 | |
| Peyton Manning | IND | QB | 24 | |
| Stephen Davis | WAS | RB | 24 | |
| Robert Smith | MIN | RB | 24 | |
| Brian Griese | DEN | QB | 23 | |
| Joe Horn | NO | WR | 23 | |
 | ||||
| Season | Player | Team | Pos | Pts |
| Marshall Faulk | STL | RB | 212 | |
| Edgerrin James | IND | RB | 200 | |
| Daunte Culpepper | MIN | QB | 196 | |
| Jeff Garcia | SF | QB | 189 | |
| Peyton Manning | IND | QB | 189 | |
| Brian Griese | DEN | QB | 185 | |
| Ricky Williams | NO | RB | 175 | |
| Stephen Davis | WAS | RB | 174 | |
| Rich Gannon | OAK | QB | 174 | |
| Charlie Garner | SF | RB | 167 |