| Week | Player | Team | Pos | Pts |
| Trent Green | STL | QB | 36 | |
| Daunte Culpepper | MIN | QB | 32 | |
| Jeff Garcia | SF | QB | 27 | |
| Mark Brunell | JAX | QB | 27 | |
| Ricky Watters | SEA | RB | 24 | |
| Robert Smith | MIN | RB | 22 | |
| Edgerrin James | IND | RB | 21 | |
| Keenan McCardell | JAX | WR | 21 | |
| Rich Gannon | OAK | QB | 20 | |
| Steve McNair | TEN | QB | 20 | |
 | ||||
| Season | Player | Team | Pos | Pts |
| Daunte Culpepper | MIN | QB | 228 | |
| Edgerrin James | IND | RB | 221 | |
| Jeff Garcia | SF | QB | 216 | |
| Marshall Faulk | STL | RB | 212 | |
| Peyton Manning | IND | QB | 202 | |
| Brian Griese | DEN | QB | 201 | |
| Rich Gannon | OAK | QB | 194 | |
| Charlie Garner | SF | RB | 186 | |
| Ricky Williams | NO | RB | 186 | |
| Stephen Davis | WAS | RB | 174 |