| Week | Player | Team | Pos | Pts |
| Corey Dillon | CIN | RB | 37 | |
| Kerry Collins | NYJ | QB | 26 | |
| Isaac Bruce | STL | WR | 23 | |
| Aaron Brooks | NO | QB | 22 | |
| Trent Green | KC | QB | 22 | |
| Doug Flutie | SD | QB | 22 | |
| Rod Smith | DEN | WR | 21 | |
| Peerless Price | BUF | WR | 21 | |
| Garrison Hearst | SF | RB | 20 | |
| Anthony Thomas | CHI | RB | 20 | |
 | ||||
| Season | Player | Team | Pos | Pts |
| Daunte Culpepper | MIN | QB | 162 | |
| Kurt Warner | STL | QB | 133 | |
| Jeff Garcia | SF | QB | 132 | |
| Curtis Martin | NYJ | RB | 122 | |
| Peyton Manning | IND | QB | 118 | |
| Donovan McNabb | PHI | QB | 115 | |
| Rod Smith | DEN | WR | 111 | |
| Brett Favre | GB | QB | 109 | |
| LaDainian Tomlinson | SD | RB | 108 | |
| Brian Griese | DEN | QB | 107 |