| Week | Player | Team | Pos | Pts |
| Randy Moss | MIN | WR | 36 | |
| Marty Booker | CHI | WR | 34 | |
| Jerry Rice | OAK | WR | 31 | |
| Rich Gannon | OAK | QB | 28 | |
| Aaron Brooks | NO | QB | 26 | |
| Kurt Warner | STL | QB | 26 | |
| Daunte Culpepper | MIN | QB | 24 | |
| Jeff Garcia | SF | QB | 22 | |
| Ricky Williams | NO | RB | 22 | |
| Marshall Faulk | STL | RB | 21 | |
 | ||||
| Season | Player | Team | Pos | Pts |
| Daunte Culpepper | MIN | QB | 208 | |
| Jeff Garcia | SF | QB | 198 | |
| Peyton Manning | IND | QB | 174 | |
| Donovan McNabb | PHI | QB | 174 | |
| Aaron Brooks | NO | QB | 167 | |
| Kurt Warner | STL | QB | 163 | |
| Curtis Martin | NYJ | RB | 163 | |
| Rich Gannon | OAK | QB | 161 | |
| Brett Favre | GB | QB | 151 | |
| Brian Griese | DEN | QB | 151 |