| Week | Player | Team | Pos | Pts |
| Jamal Anderson | ATL | RB | 38 | |
| Charles Johnson | PIT | WR | 33 | |
| Antonio Freeman | GB | WR | 31 | |
| Fred Taylor | JAX | RB | 27 | |
| Terrell Davis | DEN | RB | 26 | |
| Jim Harbaugh | BAL | QB | 26 | |
| Trent Green | WAS | QB | 23 | |
| Jake Reed | MIN | WR | 23 | |
| Neil O'Donnell | CIN | QB | 22 | |
| Eddie George | TEN | RB | 22 | |
 | ||||
| Season | Player | Team | Pos | Pts |
| Steve Young | SF | QB | 226 | |
| Terrell Davis | DEN | RB | 201 | |
| Jamal Anderson | ATL | RB | 143 | |
| Brett Favre | GB | QB | 134 | |
| Mark Brunell | JAX | QB | 133 | |
| Robert Smith | MIN | RB | 130 | |
| Randall Cunningham | MIN | QB | 129 | |
| Antonio Freeman | GB | WR | 128 | |
| Drew Bledsoe | NE | QB | 126 | |
| Garrison Hearst | SF | RB | 125 |