| Week | Player | Team | Pos | Pts |
| O.J. McDuffie | MIA | WR | 25 | |
| Ricky Watters | SEA | RB | 23 | |
| Kordell Stewart | PIT | QB | 23 | |
| Vinny Testeverde | NYJ | QB | 22 | |
| Jamal Anderson | ATL | RB | 22 | |
| Terrell Owens | SF | WR | 21 | |
| Steve McNair | TEN | QB | 21 | |
| Trent Dilfer | TB | QB | 20 | |
| Tony Banks | STL | QB | 20 | |
| Seattle | SEA | ST/D | 20 | |
| Season | Player | Team | Pos | Pts |
| Steve Young | SF | QB | 226 | |
| Terrell Davis | DEN | RB | 220 | |
| Jamal Anderson | ATL | RB | 165 | |
| Robert Smith | MIN | RB | 149 | |
| Brett Favre | GB | QB | 147 | |
| Steve McNair | TEN | QB | 145 | |
| Mark Brunell | JAX | QB | 143 | |
| Barry Sanders | DET | RB | 141 | |
| Drew Bledsoe | NE | QB | 140 | |
| Marshall Faulk | IND | RB | 139 |