| Week | Player | Team | Pos | Pts |
| Fred Taylor | JAX | RB | 36 | |
| Jake Plummer | AZ | QB | 32 | |
| Skip Hicks | WAS | RB | 27 | |
| New Orleans | NO | ST/D | 25 | |
| Steve Young | SF | QB | 24 | |
| Reidel Anthony | TB | WR | 24 | |
| Frank Sanders | AZ | WR | 24 | |
| Jerry Rice | SF | WR | 22 | |
| Jamal Anderson | ATL | RB | 22 | |
| Peyton Manning | IND | QB | 21 | |
 | ||||
| Season | Player | Team | Pos | Pts |
| Steve Young | SF | QB | 250 | |
| Terrell Davis | DEN | RB | 237 | |
| Jamal Anderson | ATL | RB | 187 | |
| Brett Favre | GB | QB | 166 | |
| Steve McNair | TEN | QB | 162 | |
| Fred Taylor | JAX | RB | 162 | |
| Mark Brunell | JAX | QB | 156 | |
| Robert Smith | MIN | RB | 155 | |
| Marshall Faulk | IND | RB | 152 | |
| Drew Bledsoe | NE | QB | 152 |