| Week | Player | Team | Pos | Pts |
| Marshall Faulk | IND | RB | 38 | |
| Randy Moss | MIN | WR | 36 | |
| Randall Cunningham | MIN | QB | 30 | |
| O.J. McDuffie | MIA | WR | 28 | |
| Peyton Manning | IND | QB | 26 | |
| Jamal Anderson | ATL | RB | 26 | |
| Curtis Martin | NYJ | RB | 26 | |
| Troy Aikman | DAL | QB | 25 | |
| Emmitt Smith | DAL | RB | 25 | |
| Doug Flutie | BUF | QB | 25 | |
 | ||||
| Season | Player | Team | Pos | Pts |
| Steve Young | SF | QB | 303 | |
| Terrell Davis | DEN | RB | 268 | |
| Jamal Anderson | ATL | RB | 220 | |
| Marshall Faulk | IND | RB | 208 | |
| Brett Favre | GB | QB | 206 | |
| Randall Cunningham | MIN | QB | 200 | |
| Drew Bledsoe | NE | QB | 198 | |
| Steve McNair | TEN | QB | 191 | |
| Mark Brunell | JAX | QB | 188 | |
| Garrison Hearst | SF | RB | 186 |