| Week | Player | Team | Pos | Pts |
| Marshall Faulk | STL | RB | 27 | |
| Ed McCaffrey | DEN | WR | 23 | |
| Jerome Bettis | PIT | RB | 23 | |
| Olindo Mare | MIA | K | 19 | |
| Randy Moss | MIN | WR | 18 | |
| Tony Martin | MIA | WR | 17 | |
| Eddie George | TEN | RB | 16 | |
| Terry Kirby | CLE | RB | 15 | |
| Drew Bledsoe | NE | QB | 14 | |
| Seattle | SEA | ST/D | 14 | |
 | ||||
| Season | Player | Team | Pos | Pts |
| Drew Bledsoe | NE | QB | 112 | |
| Stephen Davis | WAS | RB | 103 | |
| Peyton Manning | IND | QB | 101 | |
| Brad Johnson | WAS | QB | 99 | |
| Doug Flutie | BUF | QB | 99 | |
| Isaac Bruce | STL | WR | 96 | |
| Marvin Harrison | IND | WR | 96 | |
| Kurt Warner | STL | QB | 92 | |
| Eddie George | TEN | RB | 89 | |
| Randall Cunningham | MIN | QB | 88 |